MYST1 Protein, Human

The MYST1 protein is a histone acetyltransferase associated with transcriptional activation and potential regulation of gene expression. In addition to transcription, MYST1 may also affect ATM function. MYST1 Protein, Human is the recombinant human-derived MYST1 protein, expressed by E. coli , with tag free. The total length of MYST1 Protein, Human is 458 a.a., .

MYST1 Protein, identified as a histone acetyltransferase, is implicated in transcriptional activation, suggesting its potential role in modulating gene expression. Beyond its involvement in transcriptional processes, MYST1 may exert influence over the function of ATM. As a component of the MSL complex, MYST1 plays a critical role in acetylating nucleosomal histone H4, specifically generating H4K16ac, a modification associated with chromatin remodeling. Additionally, as part of the NSL complex, MYST1 may contribute to the acetylation of nucleosomal histone H4 on various lysine residues, although with less specificity compared to the MSL complex. Notably, MYST1 exhibits the capacity to acetylate TP53/p53 at 'Lys-120,' further broadening its functional repertoire in cellular processes beyond chromatin modification.

Human

E. coli

Tag Free

Q9H7Z6 (M1-K458)

84148

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.