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  3. Neuropilin-2 Protein, Mouse (864a.a, HEK293, His)

Neuropilin-2 Protein, Mouse (864a.a, HEK293, His)

Cat. No.: HY-P73315
COA Handling Instructions

Neuropilin-2 protein, a high affinity receptor, binds to semaphorins 3C and 3F, VEGF-165, VEGF-145, and PLGF-2.It forms a heterodimer with NRP1 and also interacts with PLXNB1, similar to NRP1.Neuropilin-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Neuropilin-2 protein, expressed by HEK293 , with C-His labeled tag.

For research use only. We do not sell to patients.

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10 μg $112 In-stock
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  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Neuropilin-2 protein, a high affinity receptor, binds to semaphorins 3C and 3F, VEGF-165, VEGF-145, and PLGF-2.It forms a heterodimer with NRP1 and also interacts with PLXNB1, similar to NRP1.Neuropilin-2 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Neuropilin-2 protein, expressed by HEK293 , with C-His labeled tag.

Background

Neuropilin-2 protein is a high affinity receptor for semaphorins 3C and 3F, the VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF. It forms a heterodimer with NRP1 and also binds to PLXNB1, similar to NRP1.

Species

Mouse

Source

HEK293

Tag

C-His

Accession

O35375 (M1-P864)

Gene ID
Molecular Construction
N-term
Neuropilin-2 (M1-P864)
Accession # O35375
His
C-term
Synonyms
Neuropilin-2; NRP2; VEGF165R2
Molecular Weight

Approximately 96.5 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Appearance

Solution

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

Storage & Stability

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Documentation

Neuropilin-2 Protein, Mouse (864a.a, HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
Neuropilin-2 Protein, Mouse (864a.a, HEK293, His)
Cat. No.:
HY-P73315
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