1. Recombinant Proteins
  2. CD Antigens Receptor Proteins
  3. Pattern Recognition Receptors
  4. C-type Lectin Receptors
  5. CLEC2D
  6. OCIL/CLEC2D Protein, Rat (HEK293, Fc)

OCIL/CLEC2D Protein, Rat (HEK293, Fc)

Cat. No.: HY-P76831
COA Handling Instructions

The OCIL/CLEC2D protein, also known as osteoclast inhibitory lectin (OCIL) or C-type lectin domain family 2 member D (CLEC2D), functions as a lectin-type receptor located on the cell surface. Lectins are proteins that specifically bind to carbohydrates, and OCIL/CLEC2D is involved in carbohydrate recognition and signaling processes by acting as a lectin-type receptor. OCIL/CLEC2D Protein, Rat (HEK293, Fc) is the recombinant rat-derived OCIL/CLEC2D protein, expressed by HEK293 , with N-hFc labeled tag. The total length of OCIL/CLEC2D Protein, Rat (HEK293, Fc) is 136 a.a., with molecular weight of 44-54 & 36 kDa, respectively.

For research use only. We do not sell to patients.

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Description

The OCIL/CLEC2D protein, also known as osteoclast inhibitory lectin (OCIL) or C-type lectin domain family 2 member D (CLEC2D), functions as a lectin-type receptor located on the cell surface. Lectins are proteins that specifically bind to carbohydrates, and OCIL/CLEC2D is involved in carbohydrate recognition and signaling processes by acting as a lectin-type receptor. OCIL/CLEC2D Protein, Rat (HEK293, Fc) is the recombinant rat-derived OCIL/CLEC2D protein, expressed by HEK293 , with N-hFc labeled tag. The total length of OCIL/CLEC2D Protein, Rat (HEK293, Fc) is 136 a.a., with molecular weight of 44-54 & 36 kDa, respectively.

Background

OCIL/CLEC2D protein, also known as Osteoclast inhibitory lectin (OCIL) or C-type lectin domain family 2 member D (CLEC2D), functions as a lectin-type receptor that is located on the cell surface. Lectins are proteins that bind specifically to carbohydrates, and by operating as a lectin-type receptor, OCIL/CLEC2D is involved in carbohydrate recognition and signaling processes. Based on its classification as a lectin-type receptor, it is likely involved in mediating cellular interactions, adhesion, or immune responses through the recognition of specific carbohydrate molecules. Further investigation is needed to fully understand the biological significance and molecular mechanisms of OCIL/CLEC2D protein.

Biological Activity

Measured by its binding ability in a functional ELISA. Immobilized Human CD161, at 10μg/mL (100 μL/well) can bind Rat OCIL. The ED50 for this effect is 3.446 μg/mL.

Species

Rat

Source

HEK293

Tag

N-hFc

Accession

Q925N7 (K98-L233)

Gene ID
Molecular Construction
N-term
hFc
OCIL (K98-L233)
Accession # Q925N7
C-term
Synonyms
C-type lectin domain family 2 member D5; Osteoclast inhibitory lectin; Ocil; Clec2d5
AA Sequence

KKTAQISTINTYAACPRNWIGVGNKCFYFNEIPSNWTLSQTLCKEQGAELARFDTEEELNFLRRYKGSSGYWFGLHRESSAHPWKWTDNTEYNNSVSIGGDEKHGFLSDNGFSSGRGYIVRKSICRKPNSYTSQCL

Molecular Weight

Approximately 43-55 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE

Appearance

Lyophilized powder

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Storage & Stability

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation

OCIL/CLEC2D Protein, Rat (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
OCIL/CLEC2D Protein, Rat (HEK293, Fc)
Cat. No.:
HY-P76831
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