2. Recombinant Proteins
  3. Enzymes & Regulators
  4. PADI2 Protein, Human (HEK293, His)

PADI2 Protein, Human (HEK293, His)

Cat. No.: HY-P78738
Handling Instructions

The PADI2 protein serves as a catalyst for the deimination process, specifically targeting arginine residues within proteins and facilitating their conversion. PADI2 Protein, Human (HEK293, His) is the recombinant human-derived PADI2 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of PADI2 Protein, Human (HEK293, His) is 665 a.a., with molecular weight of 66-85 kDa.

For research use only. We do not sell to patients.

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Description

The PADI2 protein serves as a catalyst for the deimination process, specifically targeting arginine residues within proteins and facilitating their conversion. PADI2 Protein, Human (HEK293, His) is the recombinant human-derived PADI2 protein, expressed by HEK293 , with C-10*His labeled tag. The total length of PADI2 Protein, Human (HEK293, His) is 665 a.a., with molecular weight of 66-85 kDa.
Background

PADI2 Protein, an enzyme, plays a crucial role in post-translational modifications of proteins. Dysregulation of PADI2 Protein has been associated with autoimmune disorders and inflammatory diseases. Targeting PADI2 Protein may offer potential therapeutic interventions in these conditions by modulating protein modifications, suppressing autoimmune responses, and managing inflammatory disorders.
Species

Human
Source

HEK293
Tag

C-10*His
Accession

Q9Y2J8-1 (M1-P665)
Gene ID

11240  [NCBI] 
Molecular Construction
N-term
PADI2 (M1-P665)
Accession # Q9Y2J8-1
10*His
C-term
Synonyms
PADI2; PAD-H19; KIAA0994; PAD2; PDI2
Molecular Weight

66-85 kDa
Purity

Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin Level

<0.01 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

PADI2 Protein, Human (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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