PCDH10 Protein, Human (L405P, HEK293, His)

The PCDH10 protein is a putative calcium-dependent cell adhesion protein implicated in mediating cell-cell interactions. Its response to intracellular calcium levels is characteristic of cell adhesion molecules, suggesting a role in cell recognition, adhesion and signaling. PCDH10 Protein, Human (L405P, HEK293, His) is the recombinant human-derived PCDH10 protein, expressed by HEK293 , with C-6*His labeled tag and L405P mutation.

PCDH10 Protein presents itself as a potential calcium-dependent cell-adhesion protein, suggesting a role in mediating cell-cell interactions. The protein's calcium dependence implies its responsiveness to intracellular calcium levels, which is a characteristic feature of many cell-adhesion molecules involved in processes such as cell recognition, adhesion, and signaling. PCDH10's putative function as a cell-adhesion protein suggests its involvement in maintaining tissue integrity and regulating cellular behavior within diverse biological contexts. Further exploration of its molecular interactions and cellular functions may offer valuable insights into its specific roles in cell adhesion and its potential implications in various physiological processes.

Human

HEK293

C-6*His

Q9P2E7-1 (Q19-T715, L405P)

57575  [NCBI]

QLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRPKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLT

Approximately 93.6 kDa

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.