PFDN1 Protein, Human (His)

PFDN1 Protein is pivotal in protein folding, binding specifically to cytosolic chaperonin (c-CPN) and aiding the transfer of target proteins. It also binds nascent polypeptide chains, facilitating their folding amidst diverse alternative pathways. Structurally, PFDN1 forms a heterohexamer with two PFD-alpha type and four PFD-beta type subunits. PFDN1 Protein, Human (His) is the recombinant human-derived PFDN1 protein, expressed by E. coli , with N-His labeled tag. The total length of PFDN1 Protein, Human (His) is 122 a.a., with molecular weight of ~17 kDa.

PFDN1 protein plays a crucial role in protein folding as it specifically binds to cytosolic chaperonin (c-CPN) and facilitates the transfer of target proteins to it. It also binds to nascent polypeptide chains, aiding in their folding process within an environment where numerous alternative pathways for nonnative proteins exist. Structurally, PFDN1 protein forms a heterohexamer consisting of two PFD-alpha type and four PFD-beta type subunits.

Human

E. coli

N-His

O60925 (M1-Q122)

5201  [NCBI]

Approximately 17 kDa

Greater than 95% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.