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  3. PILR-alpha Protein, Mouse (HEK293, His)

PILR-alpha Protein, Mouse (HEK293, His)

Cat. No.: HY-P76545
COA Handling Instructions

PILR-alpha Protein, a key member of paired immune system regulators, acts as a receptor for CD99 and PIANP. Its interactions with CD99 highlight its role in cellular recognition and immune response modulation. Paired receptors, featuring activating and inhibitory forms, finely tune immune system regulation. PILR-alpha's observed ligand interactions underscore its importance in mediating immune responses and cellular recognition processes. PILR-alpha Protein, Mouse (HEK293, His) is the recombinant mouse-derived PILR-alpha protein, expressed by HEK293 , with C-His labeled tag.

For research use only. We do not sell to patients.

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Size Price Stock Quantity
10 μg $85 In-stock
50 μg $240 In-stock
100 μg $380 In-stock
> 100 μg   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

PILR-alpha Protein, a key member of paired immune system regulators, acts as a receptor for CD99 and PIANP. Its interactions with CD99 highlight its role in cellular recognition and immune response modulation. Paired receptors, featuring activating and inhibitory forms, finely tune immune system regulation. PILR-alpha's observed ligand interactions underscore its importance in mediating immune responses and cellular recognition processes. PILR-alpha Protein, Mouse (HEK293, His) is the recombinant mouse-derived PILR-alpha protein, expressed by HEK293 , with C-His labeled tag.

Background

PILR-alpha Protein, a member of paired receptors pivotal in immune system regulation, serves as a receptor for CD99 and PIANP. Its involvement in interactions with CD99 underscores its role in cellular recognition and immune response modulation. Paired receptors, characterized by closely related activating and inhibitory forms, play a crucial role in finely tuning the regulatory mechanisms of the immune system. The observed interactions with specific ligands emphasize PILR-alpha's significance in mediating immune responses and cellular recognition processes.

Biological Activity

Measured by its binding ability in a functional ELISA. Immobilized recombinant mouse PILRA at 20 μg/mL (100 μl/well) can bind mouse CD99 . The EC50 of mouse CD99 is ≤2 μg/mL.

Species

Mouse

Source

HEK293

Tag

C-His

Accession

Q2YFS3 (E32-V197)

Gene ID
Molecular Construction
N-term
PILR-alpha (E32-V197)
Accession # Q2YFS3
His
C-term
Synonyms
Paired immunoglobulin-like type 2 receptor alpha; Cell surface receptor FDF03; PILRA
Molecular Weight

35-45 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE

Appearance

Solution

Formulation

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

N/A.

Storage & Stability

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Documentation

PILR-alpha Protein, Mouse (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
PILR-alpha Protein, Mouse (HEK293, His)
Cat. No.:
HY-P76545
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