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PLAU/uPA Protein, Cynomolgus (HEK293, His)

Cat. No.: HY-P700811
Handling Instructions

PLAU, also known as uPA (urokinase plasminogen activator), exhibits defects in conserved residues critical for propagation feature annotation. This defect in the PLAU/uPA protein prevents the propagation of specific functional characteristics associated with this protein. PLAU/uPA Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived PLAU/uPA protein, expressed by HEK293 , with C-His labeled tag. The total length of PLAU/uPA Protein, Cynomolgus (HEK293, His) is 410 a.a., with molecular weight of 23-25 kDa (long chain A), 35-40 kDa (cha.

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Description

PLAU, also known as uPA (urokinase plasminogen activator), exhibits defects in conserved residues critical for propagation feature annotation. This defect in the PLAU/uPA protein prevents the propagation of specific functional characteristics associated with this protein. PLAU/uPA Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived PLAU/uPA protein, expressed by HEK293 , with C-His labeled tag. The total length of PLAU/uPA Protein, Cynomolgus (HEK293, His) is 410 a.a., with molecular weight of 23-25 kDa (long chain A), 35-40 kDa (cha.

Background

PLAU, also known as uPA (urokinase plasminogen activator), exhibits a deficiency in the conserved residue(s) crucial for propagating feature annotation. This deficiency in PLAU/uPA protein hampers the propagation of specific functional characteristics associated with this protein. PLAU/uPA is a serine protease that functions in the plasminogen activation system, playing a pivotal role in the regulation of fibrinolysis and extracellular matrix remodeling. It converts plasminogen into plasmin, a protease that degrades fibrin clots and various extracellular matrix components. PLAU/uPA is involved in processes such as tissue remodeling, cell migration, angiogenesis, and cellular invasion. The deficiency of the conserved residue(s) in PLAU/uPA protein may have significant implications for fibrinolysis regulation and extracellular matrix dynamics, warranting further investigation into the functional consequences of this deficiency on the protein's biological activities.

Species

Cynomolgus

Source

HEK293

Tag

C-His

Accession

A0A2K5WND1 (S21-L430)

Gene ID

102135886

Molecular Construction
N-term
PLAU (S21-L430)
Accession # A0A2K5WND1
His
C-term
Synonyms
PLAU; Urokinase; ATF; UPA; URK; u-PA; BDPLT5; QPD
Molecular Weight

23-25 kDa (long chain A), 35-40 kDa (cha

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

PLAU/uPA Protein, Cynomolgus (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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PLAU/uPA Protein, Cynomolgus (HEK293, His)
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HY-P700811
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