PSG1 Protein, Human (HEK 293, hFc)

Pregnancy-specific beta-1-glycoprotein 1 (PSG1) is derived from the syncytiotrophoblast and reaches concentrations in the serum of term pregnant women of 100 to 290 mg/l. As an important component of the human placenta, PSG1's molecular signature within the immunoglobulin (Ig) superfamily contributes to its important role in supporting pregnancy. PSG1 Protein, Human (HEK 293, hFc) is the recombinant human-derived PSG1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of PSG1 Protein, Human (HEK 293, hFc) is 385 a.a., with molecular weight of ~95 KDa.

Pregnancy-specific beta-1-glycoprotein 1 (PSG1) is a prominent constituent of the human placenta, a vital endocrine organ crucial for sustaining fetal well-being. Originating from the syncytiotrophoblast, PSG1 attains concentrations of 100 to 290 mg/l in the serum of pregnant women at term. Classified within the immunoglobulin (Ig) superfamily, PSG1's molecular characteristics contribute to its essential role in supporting pregnancy. With a restricted expression primarily localized to the placenta (RPKM 224.3), PSG1 underscores its significance as a major contributor to the hormonal milieu essential for fetal survival and development during pregnancy.

Human

HEK293

C-hFc

NP_001171754.1 (Q35-P419)

5669

Approximately 95 kDa.

• 
  Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.