1. Recombinant Proteins
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  3. Transferases (EC 2)
  4. RPS6KA6 Protein, Human (sf9, GST)

RSK4 (ribosomal S6 kinase 4) is a serine/threonine protein kinase that is constitutively active and does not require the presence of growth factors to function. It is involved in cell signaling pathways related to cell growth arrest, especially those mediated by p53/TP53 proteins. RPS6KA6 Protein, Human (sf9, GST) is the recombinant human-derived RPS6KA6, expressed by Sf9 insect cells , with GST labeled tag. ,

For research use only. We do not sell to patients.

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Description

RSK4 (ribosomal S6 kinase 4) is a serine/threonine protein kinase that is constitutively active and does not require the presence of growth factors to function. It is involved in cell signaling pathways related to cell growth arrest, especially those mediated by p53/TP53 proteins. RPS6KA6 Protein, Human (sf9, GST) is the recombinant human-derived RPS6KA6, expressed by Sf9 insect cells , with GST labeled tag. ,

Background

RSK4 (Ribosomal S6 kinase 4) is a serine/threonine-protein kinase that exhibits constitutive activity and does not require the presence of growth factors to function. It is involved in cellular signaling pathways related to cell growth arrest, particularly those mediated by the p53/TP53 protein. RSK4 is thought to play a role in inhibiting cell growth during embryogenesis, suggesting its importance in regulating development processes. By understanding the function and regulation of RSK4, we can gain insights into the mechanisms underlying cell growth control and potential implications in embryonic development and related disorders.

Species

Human

Source

Sf9 insect cells

Tag

GST

Accession

Q9UK32 (M1-L745)

Gene ID

27330

Synonyms
RPS6KA6; ribosomal protein S6 kinase, 90kDa, polypeptide 6; ribosomal protein S6 kinase, 90kD, polypeptide 6; ribosomal protein S6 kinase alpha-6; RSK4; RSK-4; p90RSK6; p90-RSK 6; S6K-alpha 6; S6K-alpha-6; ribosomal S6 kinase 4; 90 kDa ribosomal protein S6 kinase 6; PP90RSK4
Purity

Greater than 80 % as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

RPS6KA6 Protein, Human (sf9, GST) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
RPS6KA6 Protein, Human (sf9, GST)
Cat. No.:
HY-P702651
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