Semaphorin-3C/SEMA3C Protein, Human (HEK293, His)

Semaphorin-3C (SEMA3C) protein plays a crucial role in developmental processes by binding to plexin family members, particularly PLXND1, orchestrating intricate cellular signaling pathways. Its indispensable contribution to normal cardiovascular development during embryogenesis and its function as an attractant for growing axons underscore SEMA3C's significance in axon growth and guidance. Semaphorin-3C/SEMA3C Protein, Human (HEK293, His) is the recombinant human-derived Semaphorin-3C/SEMA3C protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Semaphorin-3C/SEMA3C Protein, Human (HEK293, His) is 718 a.a., with molecular weight of 75-120 & 27 kDa, respectively.

Semaphorin-3C (SEMA3C) protein serves as a pivotal regulator in developmental processes by binding to members of the plexin family. Crucially, SEMA3C is indispensable for normal cardiovascular development in embryogenesis. Its functionality extends to acting as an attractant for growing axons, thereby playing a significant role in axon growth and guidance. In molecular interactions, SEMA3C forms a specific association with PLXND1, highlighting its involvement in intricate cellular signaling pathways that contribute to the orchestration of developmental events.

Human

HEK293

C-6*His

Q99985 (G21-S738)

10512  [NCBI]

GSSQPQARVYLTFDELRETKTSEYFSLSHHPLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEALSVFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDKWSPWTWASSVRALPFHPKDIMGAFSHSEMQMINQYCKDTRQQHQQGDESQKMRGDYGKLKALINS

75-120&27 kDa

Greater than 95% as determined by reducing SDS-PAGE.

Solution

Supplied as a 0.2 μm filter Solution of 20 mM NaH₂PO₄, 150 mM NaCl, 0.1 M Arginine, 0.1 M Glu, 10% Glycerol, 0.01% Tween20, 5% Trehalose, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.