Serpin B12 Protein, Mouse (sf9, His)

Serpin B12 inhibits trypsin and plasmin but not thrombin, coagulation factor Xa, and urokinase-type plasminogen activator. Additionally, it interacts with SLFN12, contributing to cellular differentiation pathways, showcasing its multifunctional nature beyond classical protease inhibition. Serpin B12 Protein, Mouse (sf9, His) is the recombinant mouse-derived Serpin B12 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Serpin B12 Protein, Mouse (sf9, His) is 423 a.a., with molecular weight of ~58 kDa.

Serpin B12, a versatile protease inhibitor, exerts inhibitory effects on trypsin and plasmin while sparing thrombin, coagulation factor Xa, and urokinase-type plasminogen activator. Beyond its role as a protease regulator, Serpin B12 is implicated in cell differentiation, where it interacts with SLFN12, contributing to a pathway that governs the intricate process of cellular differentiation. This highlights the multifunctional nature of Serpin B12, suggesting its involvement in crucial cellular processes beyond its classical role as a protease inhibitor.

Mouse

Sf9 insect cells

C-His

Q9D7P9 (M1-P423)

71869  [NCBI]

Approximately 58 kDa

Greater than 80% as determined by reducing SDS-PAGE

Solution.

Supplied as a 0.22 μm filtered solution in 50mM Tris,100mM NaCl,0.5mM PMSF, 10% Glycerol,pH 7.4

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.