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SFRP2 Protein, Cynomolgus (HEK293, His)

Cat. No.: HY-P700823
Handling Instructions

The SFRP2 Protein, belonging to the secreted frizzled-related protein (sFRP) family, modulates Wnt signaling pathways and cellular processes. Notably, SFRP2 lacks conserved residue(s) crucial for feature annotation propagation, suggesting unique structural or functional properties within the sFRP family. This distinctiveness in SFRP2 compared to other family members prompts exploration of its role in Wnt signaling, contributing to understanding regulatory variations. Further investigation, especially concerning the absence of conserved residues, promises insights into SFRP2's contributions to developmental processes and Wnt-influenced disease pathways. SFRP2 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived SFRP2 protein, expressed by HEK293, with C-His labeled tag. The total length of SFRP2 Protein, Cynomolgus (HEK293, His) is 271 a.a., with molecular weight of 33-38 kDa.

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Description

The SFRP2 Protein, belonging to the secreted frizzled-related protein (sFRP) family, modulates Wnt signaling pathways and cellular processes. Notably, SFRP2 lacks conserved residue(s) crucial for feature annotation propagation, suggesting unique structural or functional properties within the sFRP family. This distinctiveness in SFRP2 compared to other family members prompts exploration of its role in Wnt signaling, contributing to understanding regulatory variations. Further investigation, especially concerning the absence of conserved residues, promises insights into SFRP2's contributions to developmental processes and Wnt-influenced disease pathways. SFRP2 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived SFRP2 protein, expressed by HEK293, with C-His labeled tag. The total length of SFRP2 Protein, Cynomolgus (HEK293, His) is 271 a.a., with molecular weight of 33-38 kDa.

Background

The SFRP2 Protein is a member of the secreted frizzled-related protein (sFRP) family, indicating its involvement in modulating Wnt signaling pathways and cellular processes. However, it is noteworthy that SFRP2 lacks conserved residue(s) required for the propagation of feature annotation. This suggests unique structural characteristics or functional properties within the sFRP family, highlighting the distinctiveness of SFRP2 in comparison to other family members. The study of SFRP2 contributes to our understanding of its specific functions and interactions within the context of Wnt signaling, shedding light on potential variations in its regulatory mechanisms. Further exploration of SFRP2's role, especially regarding the absence of conserved residues, holds promise for enhancing our knowledge of its contributions to developmental processes and disease pathways influenced by Wnt signaling.

Species

Cynomolgus

Source

HEK293

Tag

C-His

Accession

G8F2Z7 (L25-C295)

Gene ID
Molecular Construction
N-term
SFRP2 (L25-C295)
Accession # G8F2Z7
His
C-term
Synonyms
sFRP-2; SARP-1; Sarp1; Sdf5; Sfrp2
Molecular Weight

33-38 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

SFRP2 Protein, Cynomolgus (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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SFRP2 Protein, Cynomolgus (HEK293, His)
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HY-P700823
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