SGK2 Protein, Human (Sf9, GST)

The SGK2 protein is a serine/threonine protein kinase that complexly regulates multiple cellular processes, overseeing ion channels, membrane transporters, and critical aspects of cell growth, survival, and proliferation. Its effects include upregulation of key components such as Na(+) and K(+) channels, amino acid and glutamate transporters, receptors, Na(+)/H(+) exchangers, and Na(+)/K(+) ATPase. SGK2 Protein, Human (Sf9, GST) is the recombinant human-derived SGK2 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of SGK2 Protein, Human (Sf9, GST) is 426 a.a., .

SGK2 Protein, a serine/threonine-protein kinase, intricately orchestrates a diverse array of cellular processes, playing a pivotal role in the regulation of ion channels, membrane transporters, and fundamental aspects of cell growth, survival, and proliferation. Its influence spans a range of key components, including the up-regulation of Na(+) channels (SCNN1A/ENAC), K(+) channels (KCNA3/Kv1.3, KCNE1, and KCNQ1), amino acid transporter (SLC6A19), glutamate transporter (SLC1A6/EAAT4), glutamate receptors (GRIA1/GLUR1 and GRIK2/GLUR6), Na(+)/H(+) exchanger (SLC9A3/NHE3), and the Na(+)/K(+) ATPase. Through its regulatory prowess, SGK2 emerges as a multifaceted kinase with a central role in maintaining the balance and functionality of essential cellular components critical for overall cellular homeostasis and function.

Human

Sf9 insect cells

N-GST

Q9HBY8 (Q2-C427)

10110

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.