1. Recombinant Proteins
  2. Enzymes & Regulators Ubiquitin Related Proteins
  3. Transferases (EC 2) Ubiquitin Enzymes
  4. E3 Ligases
  5. SH3RF3 Protein, Human (His)

SH3RF3 Protein, Human (His)

Cat. No.: HY-P701569
Handling Instructions

SH3RF3 protein is an E3 ubiquitin protein ligase that plays a key role in mediating the transfer of ubiquitin to target proteins, affecting protein degradation, cell signaling, and various biological processes. As an E3 ligase, SH3RF3 may promote ubiquitin-mediated proteasomal degradation of specific substrate proteins, thereby affecting their cellular levels and activity. SH3RF3 Protein, Human (His) is the recombinant human-derived SH3RF3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of SH3RF3 Protein, Human (His) is 881 a.a., .

For research use only. We do not sell to patients.

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Description

SH3RF3 protein is an E3 ubiquitin protein ligase that plays a key role in mediating the transfer of ubiquitin to target proteins, affecting protein degradation, cell signaling, and various biological processes. As an E3 ligase, SH3RF3 may promote ubiquitin-mediated proteasomal degradation of specific substrate proteins, thereby affecting their cellular levels and activity. SH3RF3 Protein, Human (His) is the recombinant human-derived SH3RF3 protein, expressed by E. coli , with N-6*His labeled tag. The total length of SH3RF3 Protein, Human (His) is 881 a.a., .

Background

SH3RF3 protein functions as an E3 ubiquitin-protein ligase, playing a pivotal role in mediating the transfer of ubiquitin molecules to target proteins. This enzymatic activity contributes to the regulation of protein degradation, cellular signaling, and various biological processes. As an E3 ligase, SH3RF3 likely facilitates the ubiquitin-mediated proteasomal degradation of specific substrate proteins, thereby influencing their cellular levels and activity. The precise targets and downstream effects of SH3RF3-mediated ubiquitination are areas of interest for understanding the protein's functional significance in cellular pathways and molecular mechanisms.

Species

Human

Source

E. coli

Tag

N-6*His

Accession

Q8TEJ3 (L2-F882)

Gene ID

344558

Molecular Construction
N-term
6*His
SH3RF3 (L2-F882)
Accession # Q8TEJ3
C-term
Synonyms
SH3RF3; E3 ubiquitin-protein ligase SH3RF3; Plenty of SH3s 2; SH3 domain-containing RING finger protein 3; SH3 multiple domains protein 4
Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
SH3RF3 Protein, Human (His)
Cat. No.:
HY-P701569
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