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SLC19A2 Protein, Human (Sf9, His, Strep, FLAG)

Cat. No.: HY-P702013
Handling Instructions

SLC19A2 Protein, supported by studies, crucially transports thiamine and mediates H(+)-dependent pyridoxine uptake. This dual function highlights SLC19A2's vital role in cellular processes for essential vitamin intake, emphasizing its significance in sustaining metabolic and biochemical functions. SLC19A2 Protein, Human (Sf9, His, Strep, FLAG) is the recombinant human-derived SLC19A2 protein, expressed by Sf9 insect cells , with N-Strep, C-Flag, N-8*His labeled tag. The total length of SLC19A2 Protein, Human (Sf9, His, Strep, FLAG) is 496 a.a., .

For research use only. We do not sell to patients.

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Description

SLC19A2 Protein, supported by studies, crucially transports thiamine and mediates H(+)-dependent pyridoxine uptake. This dual function highlights SLC19A2's vital role in cellular processes for essential vitamin intake, emphasizing its significance in sustaining metabolic and biochemical functions. SLC19A2 Protein, Human (Sf9, His, Strep, FLAG) is the recombinant human-derived SLC19A2 protein, expressed by Sf9 insect cells , with N-Strep, C-Flag, N-8*His labeled tag. The total length of SLC19A2 Protein, Human (Sf9, His, Strep, FLAG) is 496 a.a., .

Background

SLC19A2 Protein takes on a pivotal role as a high-affinity transporter facilitating the uptake of thiamine, as substantiated by various studies. In addition to its role in thiamine transport, this protein also mediates H(+)-dependent pyridoxine transport, contributing to the cellular uptake of pyridoxine. This dual functionality underscores the importance of SLC19A2 in the cellular processes associated with the intake of essential vitamins, emphasizing its significance in maintaining metabolic and biochemical functions.

Species

Human

Source

Sf9 insect cells

Tag

N-Strep;C-Flag;N-8*His

Accession

O60779 (D2-S497)

Gene ID

10560

Molecular Construction
N-term
8*His-Strep
SLC19A2 (D2-S497)
Accession # O60779
Flag
C-term
Synonyms
SLC19A2; Thiamine transporter 1; ThTr-1; ThTr1; Solute carrier family 19 member 2; Thiamine carrier 1; TC1
Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

SLC19A2 Protein, Human (Sf9, His, Strep, FLAG) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
SLC19A2 Protein, Human (Sf9, His, Strep, FLAG)
Cat. No.:
HY-P702013
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