SLC23A2 Protein, Human (Cell-Free, His)

The SLC23A2 protein is a sodium/ascorbic acid cotransporter that significantly promotes the electrical uptake of vitamin C, with a stoichiometry of 2 Na(+) ions per ascorbic acid molecule. Its role is critical in maintaining cellular vitamin C homeostasis, emphasizing its specific and efficient ascorbic acid transport. SLC23A2 Protein, Human (Cell-Free, His) is the recombinant human-derived SLC23A2 protein, expressed by E. coli Cell-free , with C-6*His labeled tag. The total length of SLC23A2 Protein, Human (Cell-Free, His) is 650 a.a., with molecular weight of 71.3 kDa.

SLC23A2, a sodium/ascorbate cotransporter, plays a pivotal role in the electrogenic uptake of vitamin C, demonstrating a stoichiometry of 2 Na(+) ions for each ascorbate molecule. This transporter facilitates the efficient and specific transport of ascorbate, showcasing its significance in cellular vitamin C homeostasis. The electrogenic nature of the uptake process highlights the involvement of electrical potential in the translocation of both sodium ions and ascorbate across cellular membranes, underscoring SLC23A2's crucial function in mediating the influx of vitamin C into cells.

Human

E. coli Cell-free

C-6*His

Q9UGH3 (M1-G650)

9962

MMGIGKNTTSKSMEAGSSTEGKYEDEAKHPAFFTLPVVINGGATSSGEQDNEDTELMAIYTTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGYDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTDVSVANGTAELLHTEHIWYPRIREIQGAIIMSSLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSWLLCFIFTVTDVFPPDSTKYGFYARTDARQGVLLVAPWFKVPYPFQWGLPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKVGSRRVIQCGAALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNPLVTGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIRKWKKGVGKGNKSLDGMESYNLPFGMNIIKKYRCFSYLPISPTFVGYTWKGLRKSDNSRSSDEDSQATG

71.3 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.