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Statherin Protein, Human (HEK293, Fc)

Cat. No.: HY-P76665
COA Handling Instructions

Statherin, a salivary protein, crucially regulates saliva's calcium salt supersaturation by inhibiting calcium phosphate salt precipitation. Beyond preventing crystallization, statherin significantly influences hydroxyapatite crystal formation on teeth, highlighting its dual role in dental health. It prevents undesirable mineral deposition and impacts tooth mineralization dynamics. Statherin Protein, Human (HEK293, Fc) is the recombinant human-derived Statherin protein, expressed by HEK293 , with C-mFc labeled tag. The total length of Statherin Protein, Human (HEK293, Fc) is 62 a.a., with molecular weight of ~36 KDa.

For research use only. We do not sell to patients.

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Description

Statherin, a salivary protein, crucially regulates saliva's calcium salt supersaturation by inhibiting calcium phosphate salt precipitation. Beyond preventing crystallization, statherin significantly influences hydroxyapatite crystal formation on teeth, highlighting its dual role in dental health. It prevents undesirable mineral deposition and impacts tooth mineralization dynamics. Statherin Protein, Human (HEK293, Fc) is the recombinant human-derived Statherin protein, expressed by HEK293 , with C-mFc labeled tag. The total length of Statherin Protein, Human (HEK293, Fc) is 62 a.a., with molecular weight of ~36 KDa.

Background

Statherin, a salivary protein, serves as a crucial regulator in maintaining saliva supersaturated with calcium salts by effectively inhibiting the precipitation of calcium phosphate salts. Beyond its role in preventing the unwanted crystallization of calcium phosphate, statherin plays a significant role in modulating the formation of hydroxyapatite crystals on the tooth surface. This dual function underscores the importance of statherin in dental health, contributing to the prevention of undesirable mineral deposition and influencing the dynamics of tooth mineralization.

Species

Human

Source

HEK293

Tag

C-mFc

Accession

P02808-1 (M1-F62)

Gene ID
Molecular Construction
N-term
Statherin (M1-F62)
Accession # P02808-1
mFc
C-term
Synonyms
Statherin; STATH
AA Sequence

MKFLVFAFILALMVSMIGADSSEEKFLRRIGRFGYGYGPYQPVPEQPLYPQPYQPQYQQYTF

Molecular Weight

Approximately 36 kDa.

Purity

Greater than 95% as determined by reducing SDS-PAGE

Appearance

Solution.

Formulation

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

N/A.

Storage & Stability

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Documentation

Statherin Protein, Human (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
Statherin Protein, Human (HEK293, Fc)
Cat. No.:
HY-P76665
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