Syndecan-1/CD138 Protein, Human (Biotinylated, HEK293, His-Avi)

Syndecan-1/CD138 Protein, a cell surface proteoglycan, connects the cytoskeleton to the interstitial matrix with heparan sulfate and chondroitin sulfate. It regulates exosome biogenesis with SDCBP and PDCD6IP. Syndecan-1/CD138 Protein induces its own expression through an MSX1 pathway in dental cells and interacts with CDCP1 and TIAM1. It also interacts with MDK, participating in diverse cellular processes. Syndecan-1/CD138 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived Syndecan-1/CD138 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of Syndecan-1/CD138 Protein, Human (Biotinylated, HEK293, His-Avi) is 232 a.a., with molecular weight of 50-70 kDa.

Syndecan-1/CD138 Protein is a cell surface proteoglycan characterized by the presence of heparan sulfate and chondroitin sulfate, which enables its role in connecting the cytoskeleton to the interstitial matrix. It collaborates with SDCBP and PDCD6IP to regulate exosome biogenesis. Furthermore, Syndecan-1/CD138 Protein has the ability to induce its own expression not only in dental mesenchymal cells but also in adjacent dental epithelial cells through an MSX1-mediated pathway. It interacts with CDCP1 and TIAM1, specifically through its C-terminus and the PDZ domain of TIAM1, respectively. Additionally, Syndecan-1/CD138 Protein interacts with MDK, facilitating its involvement in various cellular processes.

Human

HEK293

C-Avi;C-His

P18827 (Q23-G254)

6382  [NCBI]

50-70 kDa

Greater than 95% as determined by Tris-Bis PAGE

<1 EU/μg, determined by LAL method.