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  5. Syndecan-1/CD138 Protein, Mouse (HEK293, Fc)

Syndecan-1/CD138 Protein, Mouse (HEK293, Fc)

Cat. No.: HY-P77853
COA Handling Instructions

Syndecan-1/CD138 Protein, a cell surface proteoglycan, connects the cytoskeleton to the interstitial matrix.It collaborates with SDCBP and PDCD6IP to regulate exosome biogenesis.It induces its own expression in dental cells through an MSX1 pathway.It interacts with CDCP1 and TIAM1, binding to the PDZ domain of TIAM1.It also interacts with MDK, impacting cellular processes.Syndecan-1/CD138 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Syndecan-1/CD138 protein, expressed by HEK293 , with C-hFc labeled tag.

For research use only. We do not sell to patients.

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Size Price Stock Quantity
20 μg $165 In-stock
50 μg $315 In-stock
100 μg $500 In-stock
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  • Biological Activity

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Description

Syndecan-1/CD138 Protein, a cell surface proteoglycan, connects the cytoskeleton to the interstitial matrix.It collaborates with SDCBP and PDCD6IP to regulate exosome biogenesis.It induces its own expression in dental cells through an MSX1 pathway.It interacts with CDCP1 and TIAM1, binding to the PDZ domain of TIAM1.It also interacts with MDK, impacting cellular processes.Syndecan-1/CD138 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Syndecan-1/CD138 protein, expressed by HEK293 , with C-hFc labeled tag.

Background

Syndecan-1/CD138 Protein is a cell surface proteoglycan that incorporates both heparan sulfate and chondroitin sulfate, playing a crucial role in connecting the cytoskeleton to the interstitial matrix. It collaborates with SDCBP and PDCD6IP to regulate the biogenesis of exosomes. Additionally, Syndecan-1/CD138 Protein has the ability to trigger its own expression in dental mesenchymal cells and neighboring dental epithelial cells through an MSX1-mediated pathway. It interacts with CDCP1 and TIAM1, specifically binding to the PDZ domain of TIAM1 via its C-terminus. Furthermore, Syndecan-1/CD138 Protein interacts with MDK, contributing to various cellular processes.

Species

Mouse

Source

HEK293

Tag

C-hFc

Accession

P18828 (Q23-G255)

Gene ID
Molecular Construction
N-term
CD138 (Q23-G255)
Accession # P18828
hFc
C-term
Synonyms
Syndecan-1; SYND1; CD138; SDC1; SDC; SDC1
Molecular Weight

85-110 kDa

Purity

Greater than 90% as determined by Tris-Bis PAGE.

Appearance

Lyophilized powder

Formulation

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

Storage & Stability

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation

Syndecan-1/CD138 Protein, Mouse (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
Syndecan-1/CD138 Protein, Mouse (HEK293, Fc)
Cat. No.:
HY-P77853
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