2. Recombinant Proteins
  3. Others
  4. Testican 3/SPOCK3 Protein, Mouse (HEK293, His)

Testican 3/SPOCK3 Protein, Mouse (HEK293, His)

Cat. No.: HY-P71352
Handling Instructions

Testican 3/SPOCK3 Protein potentially participates in diverse neurogenesis steps, indicating a multifaceted role in neural cell development. It inhibits pro-matrix metalloproteinase 2 (MMP-2) processing by MT1-MMP and MT3-MMP, regulating MMP-2 activity. Testican 3/SPOCK3's similarity to other proteins suggests interference with tumor invasion. Its comprehensive functions underscore significance in neurodevelopment and potential involvement in regulating extracellular matrix dynamics related to tumor invasion. Testican 3/SPOCK3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Testican 3/SPOCK3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Testican 3/SPOCK3 Protein, Mouse (HEK293, His) is 414 a.a., with molecular weight of 58-60 kDa.

For research use only. We do not sell to patients.

Surface Plasmon Resonance (SPR) Assay Service   Protein Expression Service

Size Stock
50 μg   Get quote  
100 μg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Testican 3/SPOCK3 Protein potentially participates in diverse neurogenesis steps, indicating a multifaceted role in neural cell development. It inhibits pro-matrix metalloproteinase 2 (MMP-2) processing by MT1-MMP and MT3-MMP, regulating MMP-2 activity. Testican 3/SPOCK3's similarity to other proteins suggests interference with tumor invasion. Its comprehensive functions underscore significance in neurodevelopment and potential involvement in regulating extracellular matrix dynamics related to tumor invasion. Testican 3/SPOCK3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Testican 3/SPOCK3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Testican 3/SPOCK3 Protein, Mouse (HEK293, His) is 414 a.a., with molecular weight of 58-60 kDa.
Background

Testican 3/SPOCK3 protein is implicated in potentially participating in diverse steps of neurogenesis, suggesting its multifaceted role in the intricate processes of neural cell development. Additionally, it inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP, indicating a regulatory function in the modulation of MMP-2 activity. Furthermore, Testican 3/SPOCK3 may interfere with tumor invasion, as suggested by similarity with other proteins. The comprehensive functions attributed to Testican 3/SPOCK3 underscore its significance in both neurodevelopmental processes and potential involvement in the regulation of extracellular matrix dynamics related to tumor invasion.
Species

Mouse
Source

HEK293
Tag

C-6*His
Accession

Q8BKV0-1 (A23-I436)
Gene ID
Molecular Construction
N-term
SPOCK3 (A23-I436)
Accession # Q8BKV0-1
6*His
C-term
Synonyms
Testican-3; Spock3
AA Sequence

AAAVAVAGGRSDGGNFLDEKQWLTTISQYDKEVGQWNKFRDEVEDDYFRTWNPGKPFDQALDPAKDPCLKTKCSRHKVCITQDAQTALCISHRRLTHSMKEVGGSHKQWRGLPSSTCKPCPIAYASPVCGSDGHSYSSQCKLEYQACVLGKQISIKCEGRCPCPSDKSMNIGRNVKRACSDLEFREVANRLRDWFKALHESGSQNKKTKALLRPERSRFDTSILPICKDSLGWMFNRLDTNYDLLLDQSELGSIYLDKNEQCTKAFFNSCDTYKDSLISNNEWCYCFQRQQDPPCHTELSNIQKRQGIKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVVGSRINGVADCAIDFEISGDFASGDFREWTDDEGEEDDIMNDKDDIEDDDEDEGDDDDDGDVHDGYI

Molecular Weight

58-60 kDa
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

Testican 3/SPOCK3 Protein, Mouse (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Testican 3/SPOCK3 Protein, Mouse (HEK293, His)
Cat. No.:
HY-P71352
Quantity:
MCE Japan Authorized Agent:

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Country or Region *

Email Address *

     

Phone Number *

 

Organization Name *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.