THBS1 Protein, Mouse (His)

The THBS1 protein is a member of the thrombospondin family and plays a key role in cell-matrix interactions, angiogenesis, and tissue remodeling.THBS1 is known for its multi-receptor binding, including integrins and CD36, regulating signaling pathways related to cell adhesion, migration and survival.THBS1 Protein, Mouse (His) is the recombinant mouse-derived THBS1 protein, expressed by E.coli , with N-6*His labeled tag.

The THBS1 protein belongs to the thrombospondin family, a group of extracellular matrix proteins involved in various biological processes. THBS1 plays a crucial role in cell-matrix interactions, tissue remodeling, and angiogenesis. It is known for its ability to bind to multiple receptors, including integrins and CD36, and modulate signaling pathways involved in cell adhesion, migration, and survival. THBS1 is also implicated in the regulation of inflammation and immune responses. However, it should be noted that the THBS1 protein lacks conserved residue(s) required for the propagation of feature annotation, which may impact its function and interactions. Further research is needed to fully understand the significance of this observation and its implications for THBS1's role in physiological and pathological processes.

Mouse

E. coli

N-6*His

Q80YQ1 (N19-K350)

21825

NRIPESGGDNGVFDIFELIGGARRGPGRRLVKGQDLSSPAFRIENANLIPAVPDDKFQDLLDAVWADKGFIFLASLRQMKKTRGTLLAVERKDNTGQIFSVVSNGKAGTLDLSLSLPGKQQVVSVEEALLATGQWKSITLFVQEDRAQLYIDCDKMESAELDVPIQSIFTRDLASVARLRVAKGDVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSATNVLLTLDNNVVNGSSPAIRTNYIGHKTKDLQAICGLSCDELSSMVLELKGLRTIVTTLQDSIRKVTEENRELVSELKRPPLCFHNGVQYKNNEEWTVDSCTECHCQNSVTICK

40.6 kDa

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized from a 0.22 μm filtered solution of 10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.