TLR2 Protein, Rat (sf9, His)

TLR2 Protein cooperates with LY96 to initiate innate immune response against bacterial lipoproteins and microbial cell wall components. It also cooperates with TLR1 or TLR6 for the immune response to bacterial lipoproteins or lipopeptides. This involves NF-kappa-B activation, cytokine secretion, and induction of inflammatory response via MYD88 and TRAF6 signaling pathways. TLR2 Protein, Rat (sf9, His) is the recombinant rat-derived TLR2 protein, expressed by Sf9 insect cells , with C-His labeled tag.

The TLR2 protein functions in cooperation with LY96 to initiate the innate immune response against bacterial lipoproteins and other microbial cell wall components. It also cooperates with TLR1 or TLR6 for the innate immune response to bacterial lipoproteins or lipopeptides. This process involves the activation of NF-kappa-B, cytokine secretion, and the induction of the inflammatory response through signaling pathways involving MYD88 and TRAF6.

Rat

Sf9 insect cells

C-His

Q6YGU2 (L17-Q587)

310553  [NCBI]

Approximately 60 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.