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Transferrin Protein, Pig (HEK293, hFc)

Cat. No.: HY-P74495
Handling Instructions

Transferrin is an important iron-binding transport protein that binds two Fe(3+) ions, usually with anions such as bicarbonate. Crucially, it transports iron from the site of absorption and heme degradation to the site of storage and utilization. Transferrin Protein, Pig (HEK293, hFc) is the recombinant pig-derived Transferrin protein, expressed by HEK293 , with C-hFc labeled tag.

For research use only. We do not sell to patients.

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  • Biological Activity

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Description

Transferrin is an important iron-binding transport protein that binds two Fe(3+) ions, usually with anions such as bicarbonate. Crucially, it transports iron from the site of absorption and heme degradation to the site of storage and utilization. Transferrin Protein, Pig (HEK293, hFc) is the recombinant pig-derived Transferrin protein, expressed by HEK293 , with C-hFc labeled tag.

Background

Transferrins, as iron-binding transport proteins, exhibit the capability to bind two Fe(3+) ions, often in conjunction with the binding of an anion, typically bicarbonate. Functionally, transferrin plays a crucial role in transporting iron from sites of absorption and heme degradation to locations dedicated to storage and utilization within the body. Beyond its primary involvement in iron homeostasis, serum transferrin may play an additional role in stimulating cell proliferation. Structured as a monomer, transferrin's versatility underscores its significance in orchestrating the intricate processes of iron transport and cellular regulation, contributing to essential physiological functions within the organism.

Species

Pig

Source

HEK293

Tag

C-hFc

Accession

A0A8D0PY93/NP_001231582.1 (Q22-T715)

Gene ID
Molecular Construction
N-term
Transferrin (Q22-T715)
Accession # A0A8D0PY93/NP_001231582.1
hFc
C-term
Synonyms
Serotransferrin; Transferrin; Beta-1 metal-binding globulin; Siderophilin; TF; TRF
Molecular Weight

100-110 kDa

Purity

Greater than 88% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

Transferrin Protein, Pig (HEK293, hFc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
Transferrin Protein, Pig (HEK293, hFc)
Cat. No.:
HY-P74495
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