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  2. CAR-T Related Proteins
  3. TROP-2
  4. TROP-2 Protein, Rat (246a.a, HEK293, His)

TROP-2 Protein, Rat (246a.a, HEK293, His)

Cat. No.: HY-P78364
COA Handling Instructions

The TROP-2 protein serves as a growth factor receptor and plays a key role in mediating cellular responses related to growth regulation. This implies its importance in transducing signals that influence cell growth processes. TROP-2 Protein, Rat (246a.a, HEK293, His) is the recombinant rat-derived TROP-2 protein, expressed by HEK293 , with C-His labeled tag. The total length of TROP-2 Protein, Rat (246a.a, HEK293, His) is 246 a.a., with molecular weight of 40-50 kDa.

For research use only. We do not sell to patients.

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Size Price Stock Quantity
50 μg $240 In-stock
100 μg   Get quote  

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Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

The TROP-2 protein serves as a growth factor receptor and plays a key role in mediating cellular responses related to growth regulation. This implies its importance in transducing signals that influence cell growth processes. TROP-2 Protein, Rat (246a.a, HEK293, His) is the recombinant rat-derived TROP-2 protein, expressed by HEK293 , with C-His labeled tag. The total length of TROP-2 Protein, Rat (246a.a, HEK293, His) is 246 a.a., with molecular weight of 40-50 kDa.

Background

The TROP-2 protein appears to serve as a growth factor receptor, implying a pivotal role in mediating cellular responses related to growth regulation. This suggests that TROP-2 is integral to the transduction of signals that influence cellular growth processes. A more in-depth exploration of the specific signaling pathways and downstream effects orchestrated by TROP-2 in its capacity as a growth factor receptor could yield valuable insights into its functional significance, shedding light on potential implications for cellular development and homeostasis.

Species

Rat

Source

HEK293

Tag

C-His

Accession

Q6P9Z6 (Q25-G270)

Gene ID
Molecular Construction
N-term
TROP-2 (Q25-G270)
Accession # Q6P9Z6
His
C-term
Synonyms
EGP1; EGP-1; TROP2; GA733-1; gp50; T16; TACSTD2; TROP-2; M1S1; TACD2
Molecular Weight

40-50 kDa

Purity

Greater than 95% as determined by Tris-Bis PAGE.

Appearance

Lyophilized powder.

Formulation

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 5% trehalose is added as protectant before lyophilization.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

Storage & Stability

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation

TROP-2 Protein, Rat (246a.a, HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
TROP-2 Protein, Rat (246a.a, HEK293, His)
Cat. No.:
HY-P78364
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