TSC22/TSC22D1 Protein, Mouse (His)

TSC22D1 protein, possessing RNA polymerase II binding activity, regulates apoptotic and cell proliferation processes. It is found in the cytoplasm and nucleus and expressed in multiple structures like the alimentary system and central nervous system. With ubiquitous expression observed, TSC22D1 likely regulates diverse cellular processes across tissues. TSC22/TSC22D1 Protein, Mouse (His) is the recombinant mouse-derived TSC22/TSC22D1 protein, expressed by E. coli , with N-His labeled tag.

TSC22D1 protein is predicted to possess DNA-binding transcription activator activity, specifically for RNA polymerase II, and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Functioning upstream of processes like negative regulation of apoptotic process, positive regulation of apoptotic process, and positive regulation of cell population proliferation, it is found in both the cytoplasm and nucleus. The expression of TSC22D1 spans various structures, including the alimentary system, central nervous system, early conceptus, genitourinary system, and sensory organ. With ubiquitous expression observed in tissues like the adrenal gland and the central nervous system at embryonic day 14, TSC22D1 likely plays a regulatory role in diverse cellular processes across different tissues.

Mouse

E. coli

N-His

NP_033392 (M1-A143)

21807  [NCBI]

Approximately 17.8 kDa.

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.