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  3. Transferases (EC 2)
  4. TSSK1 Protein, Human (Sf9, GST)

TSSK1 Protein, Human (Sf9, GST)

Cat. No.: HY-P701647
Handling Instructions

The TSSK1 protein is a testis-specific serine/threonine protein kinase that plays a crucial role during late spermatogenesis, especially during cytoplasmic remodeling. It phosphorylates "Ser-288" of TSKS, which contributes to the transition of the ring structure around the base of the flagellum. TSSK1 Protein, Human (Sf9, GST) is the recombinant human-derived TSSK1 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of TSSK1 Protein, Human (Sf9, GST) is 366 a.a., .

For research use only. We do not sell to patients.

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Description

The TSSK1 protein is a testis-specific serine/threonine protein kinase that plays a crucial role during late spermatogenesis, especially during cytoplasmic remodeling. It phosphorylates "Ser-288" of TSKS, which contributes to the transition of the ring structure around the base of the flagellum. TSSK1 Protein, Human (Sf9, GST) is the recombinant human-derived TSSK1 protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of TSSK1 Protein, Human (Sf9, GST) is 366 a.a., .

Background

The TSSK1 protein, a testis-specific serine/threonine-protein kinase, emerges as a crucial factor in spermatid development, particularly in the late stages of spermatogenesis during cytoplasm reconstruction. Its role involves phosphorylating 'Ser-288' of TSKS and contributing to the transformation of a ring-shaped structure surrounding the base of the flagellum, originating from the chromatoid body. TSSK1's involvement in these intricate processes underscores its significance in the precise orchestration of events essential for spermatid maturation. This testis-specific kinase plays a vital role in the intricate molecular events that underlie spermatogenesis, contributing to the structural changes and developmental transitions necessary for the formation of mature sperm cells.

Species

Human

Source

Sf9 insect cells

Tag

N-GST

Accession

Q9BXA7 (D2-Q367)

Gene ID

83942

Molecular Construction
N-term
GST
TSSK1 (D2-Q367)
Accession # Q9BXA7
C-term
Synonyms
TSSK1B; Testis-specific serine/threonine-protein kinase 1; TSK-1; TSK1; TSSK-1; Testis-specific kinase 1; Serine/threonine-protein kinase 22A
Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

TSSK1 Protein, Human (Sf9, GST) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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TSSK1 Protein, Human (Sf9, GST)
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HY-P701647
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