TSSK4 Protein, Human (Sf9, GST)

The TSSK4 protein is a critical serine/threonine kinase that is essential for male germ cell development and contributes to mature sperm function. It may participate in the Cre/Creb signaling pathway, phosphorylate CREB1 on "Ser-133" and stimulate this pathway. TSSK4 Protein, Human (Sf9, GST) is the recombinant human-derived TSSK4 protein, expressed by Sf9 insect cells , with GST tagged. The total length of TSSK4 Protein, Human (Sf9, GST) is 327 a.a., .

TSSK4, a serine/threonine kinase, plays a pivotal role in male germ cell development and contributes to mature sperm function. It is potentially involved in the Cre/Creb signaling pathway, as suggested by its ability to phosphorylate CREB1 on 'Ser-133' in vitro and stimulate the Cre/Creb pathway in cells. Additionally, TSSK4 exhibits phosphorylation activity on CREM at 'Ser-116' in vitro. Another target of TSSK4 phosphorylation is ODF2, with 'Ser-95' being a specific phosphorylation site. These findings underscore the multifaceted involvement of TSSK4 in critical cellular processes related to male germ cell development and sperm functionality.

Human

Sf9 insect cells

GST

Q6SA08 (G2-T328)

283629

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.