Tulp1 Protein, Human (His)

The Tulp1 protein is critical for normal development and function of photoreceptor synapses, affecting long-term survival. It interacts with cytoskeletal proteins and may be involved in protein transport within photoreceptor cells. Tulp1 Protein, Human (His) is the recombinant human-derived Tulp1 protein, expressed by E. coli , with N-His labeled tag. The total length of Tulp1 Protein, Human (His) is 489 a.a., with molecular weight of 55.76 kDa.

The Tulp1 Protein is essential for the normal development of photoreceptor synapses, and it is indispensable for both the normal function and long-term survival of photoreceptor cells. It interacts with cytoskeleton proteins, suggesting a potential role in protein transport within photoreceptor cells. Tulp1 also exhibits lipid-binding capabilities, with an affinity for various phosphatidylinositols and phosphatidic acid in vitro. Additionally, Tulp1 contributes to the stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages, implicating its involvement in cellular clearance mechanisms. Tulp1 forms homodimers and may interact with proteins such as ABCF1, PSIP1, ZEB1, HMGB2, DNM1, F-actin, TUB, and TYRO3, suggesting a diverse range of potential interactions that contribute to its multifaceted role in cellular processes.

Human

E. coli

N-His

O00294-2 (M1-E489)

/

55.76 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.