USP29 Protein, Human (Sf9, FLAG)

USP29 protein, as a deubiquitinating enzyme, plays a crucial role in innate antiviral immunity by mediating "Lys-48" deubiquitination of CGAS. This effect stabilizes CGAS, an important sensor of the cellular response to viral infection, emphasizing the importance of USP29 in regulating CGAS activity. USP29 Protein, Human (Sf9, FLAG) is the recombinant human-derived USP29 protein, expressed by Sf9 insect cells , with N-Flag labeled tag. The total length of USP29 Protein, Human (Sf9, FLAG) is 921 a.a., .

The USP29 Protein, as the subject of this description, plays a significant role as a deubiquitinase in innate antiviral immunity. It mediates 'Lys-48'-linked deubiquitination of CGAS, a key player in the cellular response to viral infections, leading to the stabilization of CGAS. This regulatory function underscores the importance of USP29 in modulating the activity of CGAS, a crucial sensor in the innate immune system. By facilitating the deubiquitination of CGAS, USP29 contributes to the maintenance of its stability, thereby enhancing its effectiveness in recognizing and responding to viral threats within the cellular environment.

Human

Sf9 insect cells

N-Flag

Q9HBJ7 (I2-A922)

57663

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.