VSTM2A Protein, Human ( E84K, HEK293, His)

VSTM2A Protein, a key player in early white and brown preadipocyte differentiation, actively promotes adipogenic commitment by upregulating the transcription factor PPARG. This regulatory role operates within a BMP4-dependent signaling pathway, highlighting intricate molecular mechanisms in differentiation. Additionally, VSTM2A functions as a homodimer, suggesting involvement in complex protein-protein interactions critical for its regulatory activities. VSTM2A Protein, Human ( E84K, HEK293, His) is the recombinant human-derived VSTM2A protein, expressed by HEK293 , with C-6*His labeled tag and E84K mutation. The total length of VSTM2A Protein, Human ( E84K, HEK293, His) is 220 a.a., with molecular weight of 38-40 kDa.

VSTM2A, a key player in the early stages of white and brown preadipocyte cell differentiation, actively contributes to adipogenic commitment by upregulating the expression of the transcription factor PPARG. This regulatory role occurs within a BMP4-dependent signaling pathway, emphasizing the intricate molecular mechanisms involved in the differentiation process. Furthermore, VSTM2A functions as a homodimer, potentially indicating its involvement in complex protein-protein interactions critical for its regulatory activities.

Human

HEK293

C-6*His

Q8TAG5-2 (S25-F244, E84K)

222008  [NCBI]

SQAKFTEFPRNVTATEGQNVEMSCAFQSGSASVYLEIQWWFLRGPEDLDPGAEGAGAQVKLLPDRDPDSDGTKISTVKVQGNDISHKLQISKVRKKDEGLYECRVTDANYGELQEHKAQAYLKVNANSHARRMQAFEASPMWLQDMKPRKNVSAAIPSSIHGSANQRTHSTSSPQVVAKIPKQSPQSGMETHFEPFILPLTNAPQKGQSYRVDRFMNGDF

38-40 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.