YKT6 Protein, Human (His)

YKT6 is a vesicle soluble NSF attachment protein receptor (v-SNARE) that mediates vesicle docking and fusion in the endoplasmic reticulum to Golgi trafficking, forming a SNARE complex with GOSR1, GOSR2, and STX5. It is also involved in the transport of early/recycling endosomes to the trans-Golgi network, forming another SNARE complex with BET1L, GOSR1 and STX5. YKT6 Protein, Human (His) is the recombinant human-derived YKT6 protein, expressed by E. coli , with N-6*His labeled tag.

YKT6, a vesicular soluble NSF attachment protein receptor (v-SNARE), plays a pivotal role in mediating vesicle docking and fusion with specific acceptor cellular compartments. It functions in endoplasmic reticulum to Golgi transport, contributing to a SNARE complex alongside GOSR1, GOSR2, and STX5. Additionally, YKT6 is involved in early/recycling endosome to trans-Golgi network transport, forming another SNARE complex with BET1L, GOSR1, and STX5. Beyond its role in membrane fusion events, YKT6 exhibits S-palmitoyl transferase activity, adding a layer of complexity to its functional repertoire. Identified in two distinct SNARE complexes, YKT6's involvement underscores its significance in orchestrating vesicular trafficking and membrane fusion processes within the cellular transport network.

Human

E. coli

N-6*His

O15498-1 (M1-M198)

10652  [NCBI]

MKLYSLSVLYKGEAKVVLLKAAYDVSSFSFFQRSSVQEFMTFTSQLIVERSSKGTRASVKEQDYLCHVYVRNDSLAGVVIADNEYPSRVAFTLLEKVLDEFSKQVDRIDWPVGSPATIHYPALDGHLSRYQNPREADPMTKVQAELDETKIILHNTMESLLERGEKLDDLVSKSEVLGTQSKAFYKTARKQNSCCAIM

Approximately 28.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

Solution.

Supplied as a 0.2 μm filtered solution of 50 mM Tris, pH 8.0.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.