2. Cell Cycle/DNA Damage Anti-infection
  3. DNA/RNA Synthesis SARS-CoV
  4. Remdesivir-d5

Remdesivir-d5  (Synonyms: GS-5734-d5)

Cat. No.: HY-104077S Purity: 99.86%
COA Handling Instructions

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Remdesivir-d5 is a deuterium labeled Remdesivir. Remdesivir (GS-5734) is a nucleoside analogue, with effective antiviral activity, with EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells. Remdesivir is highly effective in the control of 2019-nCoV (COVID-19) infection in vitro[1][2].

For research use only. We do not sell to patients.

Remdesivir-d<sub>5</sub> Chemical Structure

Remdesivir-d5 Chemical Structure

Size Price Stock Quantity
100 μg USD 170 In-stock
1 mg USD 717 In-stock
5 mg USD 1650 In-stock
10 mg   Get quote  
50 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 2 publication(s) in Google Scholar

Other Forms of Remdesivir-d5:

Remdesivir-d5 Related Antibodies

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Description

Remdesivir-d5 is a deuterium labeled Remdesivir. Remdesivir (GS-5734) is a nucleoside analogue, with effective antiviral activity, with EC50s of 74 nM for SARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells. Remdesivir is highly effective in the control of 2019-nCoV (COVID-19) infection in vitro[1][2].

Molecular Weight

607.61

Formula

C27H30D5N6O8P
Unlabeled CAS

1809249-37-3
Appearance

Solid

Color

White to off-white

SMILES

C[C@H](N[P@@](OC1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])(OC[C@H]2O[C@@](C#N)(C3=CC=C4C(N)=NC=NN43)[C@H](O)[C@@H]2O)=O)C(OCC(CC)CC)=O
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (164.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 100 mg/mL (164.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6458 mL 8.2290 mL 16.4579 mL
5 mM 0.3292 mL 1.6458 mL 3.2916 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.86%

COA (252 KB) LCMS (266 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 1.6458 mL 8.2290 mL 16.4579 mL 41.1448 mL
5 mM 0.3292 mL 1.6458 mL 3.2916 mL 8.2290 mL
10 mM 0.1646 mL 0.8229 mL 1.6458 mL 4.1145 mL
15 mM 0.1097 mL 0.5486 mL 1.0972 mL 2.7430 mL
20 mM 0.0823 mL 0.4114 mL 0.8229 mL 2.0572 mL
25 mM 0.0658 mL 0.3292 mL 0.6583 mL 1.6458 mL
30 mM 0.0549 mL 0.2743 mL 0.5486 mL 1.3715 mL
40 mM 0.0411 mL 0.2057 mL 0.4114 mL 1.0286 mL
50 mM 0.0329 mL 0.1646 mL 0.3292 mL 0.8229 mL
60 mM 0.0274 mL 0.1371 mL 0.2743 mL 0.6857 mL
80 mM 0.0206 mL 0.1029 mL 0.2057 mL 0.5143 mL
100 mM 0.0165 mL 0.0823 mL 0.1646 mL 0.4114 mL
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Remdesivir-d5 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Remdesivir-d5GS-5734-d5DNA/RNA SynthesisSARS-CoVSARS coronavirusantiviralMERS-CoV2019-nCoVCOVID-19infectionInhibitorinhibitorinhibit

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