2. Epigenetics
  3. MicroRNA
  4. Remlarsen

Remlarsen (MRG-201), a miR-29b mimic, acts a miR-29b agonist. Remlarsen has the potential for preventiong formation of a fibrotic scar or cutaneous fibrosis.

The free form of the compound is prone to instability, it is advisable to consider the stable salt form (Remlarsen sodium) that retains the same biological activity.

For research use only. We do not sell to patients.

RNA, (Am-Am-Cm-A-Cm-Um-G-Um-Um-Um-A-Cm-A-A-A-Um-G-G-Um-Cm-Cm-Um-A), 3′-[3-[[6-[(3β)-cholest-5-en-3-yloxy]hexyl]oxy]-2-hydroxypropyl hydrogen phosphate], complex with RNA ((2′-deoxy-2′-fluoro)U-A-G-(2′-deoxy-2′-fluoro)C-A-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-fluoro)C-A-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-G-A-A-A-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)C-A-G-(2′-deoxy-2′-fluoro)U-G-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-sp-U-sp-U) (1:1)

Remlarsen Chemical Structure

CAS No. : 1848266-71-6

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Other Forms of Remlarsen:

Remlarsen Related Antibodies

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Description

Remlarsen (MRG-201), a miR-29b mimic, acts a miR-29b agonist. Remlarsen has the potential for preventiong formation of a fibrotic scar or cutaneous fibrosis[1].

In Vitro

Remlarsen (MRG-201) is active in regulating PD biomarker expression in the skin[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Remlarsen Related Antibodies
Clinical Trial
Molecular Weight

16059.5 (AS: 7961.8; SS: 8097.7)

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

RNA, (Am-Am-Cm-A-Cm-Um-G-Um-Um-Um-A-Cm-A-A-A-Um-G-G-Um-Cm-Cm-Um-A), 3′-[3-[[6-[(3β)-cholest-5-en-3-yloxy]hexyl]oxy]-2-hydroxypropyl hydrogen phosphate], complex with RNA ((2′-deoxy-2′-fluoro)U-A-G-(2′-deoxy-2′-fluoro)C-A-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-fluoro)C-A-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-G-A-A-A-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)C-A-G-(2′-deoxy-2′-fluoro)U-G-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-sp-U-sp-U) (1:1)
SMILES

[Remlarsen]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (Need ultrasonic)

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Purity & Documentation
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Remlarsen Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Remlarsen1848266-71-6MRG-201MRG201MRG 201MicroRNAmiRNAmiR-29bmimicfibroticscarcutaneousInhibitorinhibitorinhibit

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