2. Neuronal Signaling
  3. Amyloid-β
  4. RI-OR2

RI-OR2, a retro-inverso peptide, is an amyloid-β (Aβ) oligomerization inhibitor. RI-OR2 binds to immobilized β-Amyloid (1-42) (HY-P1363A) monomers and fibrils, with an apparent Kd of 9-12 μM, and also acted as an inhibitor of Aβ(1-42) fibril extension.

For research use only. We do not sell to patients.

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RI-OR2 Chemical Structure

RI-OR2 Chemical Structure

CAS No. : 1219627-58-3

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RI-OR2 Related Antibodies

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Description

RI-OR2, a retro-inverso peptide, is an amyloid-β (Aβ) oligomerization inhibitor. RI-OR2 binds to immobilized β-Amyloid (1-42) (HY-P1363A) monomers and fibrils, with an apparent Kd of 9-12 μM, and also acted as an inhibitor of Aβ(1-42) fibril extension[1].

In Vitro

RI-OR2 significantly reverses the toxicity of Aβ(1-42) toward cultured SH-SY5Y neuroblastoma cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

RI-OR2 Related Antibodies
Molecular Weight

1120.35

Formula

C53H85N17O10
CAS No.
Sequence

Ac-{d-Arg}-Gly-{d-Phe}-{d-Phe}-{d-Val}-{d-Leu}-{d-Lys}-Gly-{d-Arg}-NH2
Sequence Shortening

Ac-{d-Arg}-G-{d-Phe}-{d-Phe}-{d-Val}-{d-Leu}-{d-Lys}-G-{d-Arg}-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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RI-OR2 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RI-OR21219627-58-3Amyloid-ββ-amyloid peptideAβAbetaretro-inverso peptideamyloid-β oligomerization inhibitor,Inhibitorinhibitorinhibit

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HY-P10823
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