2. Apoptosis
  3. RIP kinase
  4. RIPK2/3-IN-1

RIPK2/3-IN-1 is a potent dual RIPK2/3 kinases inhibitor with IC50 values of 3 nM and 117 nM, respectively. RIPK2/3-IN-1 is against RIPK2 with IC50 value 14 nM in 14-TriLAN-Gly/NOD1 THP-1 cell-based NF-κB reporter assay.

For research use only. We do not sell to patients.

RIPK2/3-IN-1 Chemical Structure

RIPK2/3-IN-1 Chemical Structure

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RIPK2/3-IN-1 Related Antibodies

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RIPK1 RIPK2 RIPK3

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Description

RIPK2/3-IN-1 is a potent dual RIPK2/3 kinases inhibitor with IC50 values of 3 nM and 117 nM, respectively. RIPK2/3-IN-1 is against RIPK2 with IC50 value 14 nM in 14-TriLAN-Gly/NOD1 THP-1 cell-based NF-κB reporter assay[1].

Molecular Weight

456.54

Formula

C24H16N4O2S2
SMILES

OCC1=CC=C(O1)C2=CC3=C(C=C2C4=CC=CS4)C(NC5=CC(N=CS6)=C6C=C5)=NC=N3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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RIPK2/3-IN-1 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RIPK2/3-IN-1RIP kinaseReceptor-interacting protein kinasesRIPKRIPK2/3 InhibitorInhibitorinhibitorinhibit

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