Rivoglitazone hydrochloride (Synonyms: R-106056 hydrochloride)

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Rivoglitazone hydrochloride (R-106056 hydrochloride) is a peroxisome proliferator-activated receptor-γ (PPAR-γ) agonist. Rivoglitazone hydrochloride (R-106056 hydrochloride) exerts its anti-diabetic effect by activating PPARγ to regulate the expression of a large number of genes related to lipid and glucose metabolism. Rivoglitazone hydrochloride (R-106056 hydrochloride) can be used to study insulin secretion and insulin resistance in animal models of diabetes.

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Rivoglitazone hydrochloride Chemical Structure

CAS No. : 299176-11-7

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Other Forms of Rivoglitazone hydrochloride:

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Description	Rivoglitazone hydrochloride (R-106056 hydrochloride) is a peroxisome proliferator-activated receptor-γ (PPAR-γ) agonist. Rivoglitazone hydrochloride (R-106056 hydrochloride) exerts its anti-diabetic effect by activating PPARγ to regulate the expression of a large number of genes related to lipid and glucose metabolism. Rivoglitazone hydrochloride (R-106056 hydrochloride) can be used to study insulin secretion and insulin resistance in animal models of diabetes^[1].
Molecular Weight	433.91
Formula	C₂₀H₂₀ClN₃O₄S
CAS No.	299176-11-7
SMILES	O=C(N1)SC(CC2=CC=C(OCC3=NC4=CC=C(OC)C=C4N3C)C=C2)C1=O.[H]Cl
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (265 KB) Handling Instructions (2659 KB)
References	[1]. Kanda S, et al. Potent Antidiabetic Effects of Rivoglitazone, a Novel Peroxisome Proliferator–Activated Receptor-γ Agonist, in Obese Diabetic Rodent Models[J]. Journal of pharmacological sciences, 2009, 111(2): 155-166. [Content Brief]

Rivoglitazone hydrochloride Related Classifications

Metabolic Disease

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	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rivoglitazone299176-11-7R-106056R106056R 106056PPARPeroxisome proliferator-activated receptorsGlycolipid metabolismDiabetesInsulin resistancePPARγInhibitorinhibitorinhibit

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Rivoglitazone hydrochloride (Synonyms: R-106056 hydrochloride)

Other Forms of Rivoglitazone hydrochloride:

Rivoglitazone hydrochloride Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

View All PPAR Isoform Specific Products:

Biological Activity

Purity & Documentation

References

Customer Review