1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. nAChR
  3. Rivanicline

Rivanicline  (Synonyms: RJR-2403; (E)-Metanicotine)

Cat. No.: HY-13225A
Handling Instructions

Rivanicline (RJR-2403; (E)-Metanicotine) is a neuronal nicotinic receptor (neuronal nicotinic receptor) agonist that is highly selective for the α4β2 subtype,Ki is 26 nM, which is more than 1000 times more inhibitory than α7 receptor.

For research use only. We do not sell to patients.

Rivanicline Chemical Structure

Rivanicline Chemical Structure

CAS No. : 15585-43-0

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Description

Rivanicline (RJR-2403; (E)-Metanicotine) is a neuronal nicotinic receptor (neuronal nicotinic receptor) agonist that is highly selective for the α4β2 subtype,Ki is 26 nM, which is more than 1000 times more inhibitory than α7 receptor[1].

Molecular Weight

162.23

Formula

C10H14N2

CAS No.
SMILES

CNCC/C=C/C1=CC=CN=C1

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Rivanicline
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