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  4. RNAse L RIBOTAC

RNAse L RIBOTAC (compound C64) is an RNA-degrading chimera which binds to a four-way RNA helix called SL5 in the 5’ UTR of the SARS-CoV-2 RNA genome and inhibits the virus replication in lung epithelial carcinoma cells. (Blue: RNA ligand (HY-168456); Black: linker (HY-130591); Pink: Rnase L ligand (HY-168457))

For research use only. We do not sell to patients.

RNAse L RIBOTAC Chemical Structure

RNAse L RIBOTAC Chemical Structure

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RNAse L RIBOTAC Related Antibodies

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Description

RNAse L RIBOTAC (compound C64) is an RNA-degrading chimera which binds to a four-way RNA helix called SL5 in the 5’ UTR of the SARS-CoV-2 RNA genome and inhibits the virus replication in lung epithelial carcinoma cells. (Blue: RNA ligand (HY-168456); Black: linker (HY-130591); Pink: Rnase L ligand (HY-168457))[1]

Molecular Weight

1073.18

Formula

C55H60N8O13S
SMILES

O=C(C(C/1=O)=C(NC2=CC=CC=C2)SC1=C/C3=CC=C(OCCOCCN4N=NC(COCCOCCOCCOCCOC5=CC6=NC(C(C7=O)=CC8=C(O7)C=C(N9CCNCC9)C=C8)=CN6C=C5)=C4)C(O)=C3)OCC
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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RNAse L RIBOTAC Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RNAse L RIBOTACPROTACsRNA-degrading chimeraRIBOTACSL5SARS-CoV-2virus replicationlung epithelial carcinomaInhibitorinhibitorinhibit

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