Roflumilast (Standard)

Cat. No.: HY-15455R Purity: ≥98%: FAQs
Handling Instructions

Molarity Calculator

Roflumilast (Standard) is the analytical standard of Roflumilast. This product is intended for research and analytical applications. Roflumilast (APTA-2217) is a selective PDE4 inhibitor with IC₅₀s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells.

For research use only. We do not sell to patients.

Roflumilast (Standard) Chemical Structure

CAS No. : 162401-32-3

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Description	Roflumilast (Standard) is the analytical standard of Roflumilast . This product is intended for research and analytical applications. Roflumilast (APTA-2217) is a selective PDE4 inhibitor with IC₅₀s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells.
Molecular Weight	403.21
Formula	C₁₇H₁₄Cl₂F₂N₂O₃
CAS No.	162401-32-3
SMILES	O=C(NC1=C(Cl)C=NC=C1Cl)C2=CC=C(OC(F)F)C(OCC3CC3)=C2
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Handling Instructions (2659 KB)

Roflumilast (Standard) Related Classifications

Inflammation/Immunology

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Roflumilast (Standard)162401-32-3Phosphodiesterase (PDE)RSVRespiratory syncytial virusInhibitorinhibitorinhibit

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Roflumilast (Standard)

Product Information

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