Rohitukine

Cat. No.: HY-119831: FAQs
Data Sheet Handling Instructions Technical Support

Rohitukine is an alkaloid with analgesic and anti-inflammatory activities.

For research use only. We do not sell to patients.

Rohitukine Chemical Structure

Size		Stock
MOQ		Minimum order quantity
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote
Other size		Get quote

Synthetic products have potential research and development risk.

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

Rohitukine is an alkaloid with analgesic and anti-inflammatory activities^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	> 10 μM Compound: 5	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 19757855]
ASPC1	GI₅₀	21 μM Compound: 1	Cytotoxicity against human AsPC1 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human AsPC1 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]
BXPC-3	GI₅₀	20 μM Compound: 1	Cytotoxicity against human BxPC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human BxPC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]
Caco-2	GI₅₀	25 μM Compound: 1	Growth inhibition of human Caco2 cells after 48 hrs by MTT assay Growth inhibition of human Caco2 cells after 48 hrs by MTT assay	[PMID: 29370702]
DU-145	GI₅₀	26 μM Compound: 1	Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]
HCT-116	IC₅₀	8.8 μM Compound: 5	Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 19757855]
HEK293	GI₅₀	> 50 μM Compound: 1	Cytotoxicity against HEK293 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against HEK293 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]
HL-60	GI₅₀	10 μM Compound: 1	Growth inhibition of human HL60 cells after 48 hrs by MTT assay Growth inhibition of human HL60 cells after 48 hrs by MTT assay	[PMID: 29370702]
HL-60	GI₅₀	10 μM Compound: 1	Cytotoxicity against human HL60 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human HL60 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]
HL-60	IC₅₀	7.5 μM Compound: 5	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 19757855]
Hs-578T	GI₅₀	20 μM Compound: 1	Cytotoxicity against human Hs578T cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human Hs578T cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]
K562	GI₅₀	24 μM Compound: 1	Cytotoxicity against human K562 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human K562 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]
LNCaP	GI₅₀	30 μM Compound: 1	Cytotoxicity against human LNCAP cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human LNCAP cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]
MCF7	IC₅₀	> 10 μM Compound: 5	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 19757855]
MCF7	GI₅₀	28 μM Compound: 1	Growth inhibition of human MCF7 cells after 48 hrs by MTT assay Growth inhibition of human MCF7 cells after 48 hrs by MTT assay	[PMID: 29370702]
MDA-MB-231	GI₅₀	13 μM Compound: 1	Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]
MDA-MB-468	GI₅₀	17 μM Compound: 1	Cytotoxicity against human MDA-MB-468 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-468 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]
MIA PaCa-2	GI₅₀	19 μM Compound: 1	Growth inhibition of human MIAPaCa2 cells after 48 hrs by MTT assay Growth inhibition of human MIAPaCa2 cells after 48 hrs by MTT assay	[PMID: 29370702]
MIA PaCa-2	GI₅₀	19 μM Compound: 1	Cytotoxicity against human MIAPaCa2 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human MIAPaCa2 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]
MOLT-4	GI₅₀	12 μM Compound: 1	Cytotoxicity against human MOLT4 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human MOLT4 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]
NCI-H226	IC₅₀	> 10 μM Compound: 5	Cytotoxicity against human NCI-H226 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H226 cells after 48 hrs by MTT assay	[PMID: 19757855]
PANC-1	GI₅₀	22 μM Compound: 1	Cytotoxicity against human PANC1 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human PANC1 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]
PC-3	GI₅₀	19 μM Compound: 1	Growth inhibition of human PC3 cells after 48 hrs by MTT assay Growth inhibition of human PC3 cells after 48 hrs by MTT assay	[PMID: 29370702]
PC-3	GI₅₀	19 μM Compound: 1	Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]
PSN1	GI₅₀	23 μM Compound: 1	Cytotoxicity against human PSN1 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human PSN1 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]
SF-295	GI₅₀	27 μM Compound: 1	Cytotoxicity against human SF295 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human SF295 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]
SF-539	GI₅₀	30 μM Compound: 1	Cytotoxicity against human SF539 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human SF539 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]
SNB-75	GI₅₀	22 μM Compound: 1	Cytotoxicity against human SNB75 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human SNB75 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]
T47D	GI₅₀	24 μM Compound: 1	Cytotoxicity against human T47D cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human T47D cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]
THP-1	GI₅₀	28 μM Compound: 1	Cytotoxicity against human THP1 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human THP1 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]
U-251	GI₅₀	32 μM Compound: 1	Cytotoxicity against human U251 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human U251 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27363938]

Molecular Weight

305.33

Formula

C₁₆H₁₉NO₅

CAS No.

71294-60-5

SMILES

O=C1C=C(OC2=C1C(O)=CC(O)=C2[C@@H]3[C@@H](CN(CC3)C)O)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Houghton P J, et al. Further chromone alkaloids from Schumanniophyton magnificum[J]. Planta Medica, 1987, 53(03): 262-264. [Content Brief]

Rohitukine Related Classifications

Inflammation/Immunology

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Rohitukine71294-60-5OthersAlkaloidsanalgesicsanti-inflammatoryInhibitorinhibitorinhibit

Your Recently Viewed Products:

Product Name

Requested Quantity *

Applicant Name *

Salutation

Email Address *

Phone Number *

Department

Organization Name *

City

State

Country or Region *

Remarks

Product Name

Lot #

Applicant Name *

Email Address *

Phone Number

Department *

Organization Name *

Country or Region *

Remarks

Name
Email *

	Sorry, but the email address you supplied was invalid.

Rohitukine

Rohitukine Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review

Rohitukine Related Classifications

Molarity Calculator

Dilution Calculator