2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  3. ROR
  4. RORγt agonist 2

RORγt agonist 2 is a potent agonist of RORγt. RORγt agonist 2 promotes the differentiation of Th17 cells and enhances the levels of pro-inflammatory cytokines, thereby increasing the cytotoxicity of lymphocytes. RORγt agonist 2 inhibits the production of regulatory T cells, which suppresses the immune response (extracted from patent WO2021136339A1, compound 17).

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RORγt agonist 2 Chemical Structure

RORγt agonist 2 Chemical Structure

CAS No. : 2663787-92-4

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RORγt agonist 2 Related Antibodies

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Description

RORγt agonist 2 is a potent agonist of RORγt. RORγt agonist 2 promotes the differentiation of Th17 cells and enhances the levels of pro-inflammatory cytokines, thereby increasing the cytotoxicity of lymphocytes. RORγt agonist 2 inhibits the production of regulatory T cells, which suppresses the immune response (extracted from patent WO2021136339A1, compound 17)[1].

Molecular Weight

585.64

Formula

C30H30F3N3O4S
CAS No.
SMILES

CC(C1N(C2=CC=C(C=C2)C(F)(F)F)C3=CC=C(C(N[C@H](C4=CC=C(C=C4)S(CC)(=O)=O)CC#N)=O)C=C3OC1)C
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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RORγt agonist 2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RORγt agonist 22663787-92-4RORγt agonist2RORγt agonist-2RORRAR-related orphan receptorRORγtTh17 cellspro-inflammatory cytokinescytotoxicitylymphocytesT cellsInhibitorinhibitorinhibit

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