2. Immunology/Inflammation
  3. Interleukin Related
  4. RPR-106541

RPR-106541 is a 17-thiosteroid. RPR 106541 has potent glucocorticosteroid activity. RPR 106541 also has demonstrable effects on carbohydrate and lipid metabolism.

For research use only. We do not sell to patients.

RPR-106541 Chemical Structure

RPR-106541 Chemical Structure

CAS No. : 159001-35-1

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RPR-106541 Related Antibodies

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IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22

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Description

RPR-106541 is a 17-thiosteroid. RPR 106541 has potent glucocorticosteroid activity. RPR 106541 also has demonstrable effects on carbohydrate and lipid metabolism[1].

IC50 & Target

IL-4

 

IL-5

 

In Vivo

RPR-106541 significantly inhibits CD4+ T-cell accumulation and eosinophil accumulation within the lungs and simultaneously inhibits expression of mRNA for interleukin (IL)-4 and IL-5 in an experimental rat model of pulmonary inflammation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

456.59

Formula

C24H34F2O4S
CAS No.
SMILES

C[C@@]12[C@@]3(SC)[C@@](O[C@H](O3)CCC)([H])C[C@@]1([H])[C@]4([H])C[C@H](F)C5=CC(CC[C@]5(C)[C@@]4(F)[C@@H](O)C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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RPR-106541 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RPR-106541159001-35-1RPR106541RPR 106541Interleukin RelatedILInhibitorinhibitorinhibit

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RPR-106541
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HY-19218
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