2. Metabolic Enzyme/Protease
  3. Phosphodiesterase (PDE)
  4. RS-25344

RS-25344 is a selective inhibitor of phosphodiesterase type IV (PDE4). RS-25344 increases intracellular cAMP (cyclic adenosine phosphate) concentration by inhibiting PDE4 activity. RS-25344 can be used in the study of inflammation, immune diseases, neurodegenerative diseases and cardiovascular diseases.

For research use only. We do not sell to patients.

RS-25344 Chemical Structure

RS-25344 Chemical Structure

CAS No. : 152814-89-6

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Description

RS-25344 is a selective inhibitor of phosphodiesterase type IV (PDE4). RS-25344 increases intracellular cAMP (cyclic adenosine phosphate) concentration by inhibiting PDE4 activity. RS-25344 can be used in the study of inflammation, immune diseases, neurodegenerative diseases and cardiovascular diseases[1].

Molecular Weight

375.34

Formula

C19H13N5O4
CAS No.
SMILES

O=C1N(C2=CC=CC([N+]([O-])=O)=C2)C3=NC=CC=C3C(N1CC4=CC=NC=C4)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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RS-25344 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RS-25344152814-89-6RS25344RS 25344Phosphodiesterase (PDE)Selective inhibitorcAMPinfertilityinflammationneurodegenerative diseasesPDE4Inhibitorinhibitorinhibit

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