2. Epigenetics Apoptosis
  3. METTL3 Apoptosis
  4. RSM3 TFA

RSM3 TFA, a stapled peptide, is a METTL3-METTL14 inhibitor with an Kd of 3.10 μM. RSM3 TFA inhibits tumor growth while induces cell apoptosis. RSM3 TFA can be used for study of cancer.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

RSM3 TFA Chemical Structure

RSM3 TFA Chemical Structure

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Based on 1 publication(s) in Google Scholar

Other Forms of RSM3 TFA:

RSM3 TFA Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE RSM3 TFA

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Description

RSM3 TFA, a stapled peptide, is a METTL3-METTL14 inhibitor with an Kd of 3.10 μM. RSM3 TFA inhibits tumor growth while induces cell apoptosis. RSM3 TFA can be used for study of cancer[1].

Molecular Weight

3049.66 (free base)

Formula

C130H218N54O26S3.xC2HF3O2
Appearance

Solid

Color

White to off-white

Sequence

Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Cys-Met-Glu-Leu-Gly-Arg-Glu-Cys-Leu-Asn-Leu-Trp-NH2 (Stapled between two Cys via bhp)
Sequence Shortening

RRRRRRRRRCMELGRECLNLW-NH2 (Stapled between two Cys via bhp)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 66.67 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
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RSM3 TFA Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RSM3RSM 3RSM-3METTL3ApoptosisMethyltransferase-like 3prostate cancerPC3DU145RNA methylationInhibitorinhibitorinhibit

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RSM3 TFA
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HY-P10387A
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