S(-)-8-OH-DPAT hydrobromide (Synonyms: S(-)-8-Hydroxy-2-dipropylaminotetralin hydrobromide)

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S(-)-8-OH-DPAT (S(-)-8-Hydroxy-2-dipropylaminotetralin) hydrobromide is an enantiomer of 8-OH-DPAT hydrobromide. 8-OH-DPAT hydrobromide is a potent, selective 5-HT_1A agonist with a pIC₅₀ of 8.19.

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S(-)-8-OH-DPAT hydrobromide Chemical Structure

CAS No. : 78095-20-2

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Other Forms of S(-)-8-OH-DPAT hydrobromide:

R(+)-8-OH-DPAT hydrobromide Get quote

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5-HT₁ Receptor 5-HT₂ Receptor 5-HT₃ Receptor 5-HT₄ Receptor 5-HT₅ Receptor 5-HT₆ Receptor 5-HT₇ Receptor 5-HT Receptor

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Description	S(-)-8-OH-DPAT (S(-)-8-Hydroxy-2-dipropylaminotetralin) hydrobromide is an enantiomer of 8-OH-DPAT hydrobromide. 8-OH-DPAT hydrobromide is a potent, selective 5-HT_1A agonist with a pIC₅₀ of 8.19^[1].
Molecular Weight	328.29
Formula	C₁₆H₂₆BrNO
CAS No.	78095-20-2
SMILES	OC1=C2C[C@@H](N(CCC)CCC)CCC2=CC=C1.Br
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (268 KB) Handling Instructions (2659 KB)
References	[1]. Wierońska JM, et al. The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT1A receptor signaling: mechanistic studies. Psychopharmacology (Berl). 2015 Jan;232(1):259-73. [Content Brief]

S(-)-8-OH-DPAT hydrobromide Related Classifications

Neurological Disease

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

S(-)-8-OH-DPAT78095-20-2S(-)-8-Hydroxy-2-dipropylaminotetralin5-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorAgonistInhibitorinhibitorinhibit

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S(-)-8-OH-DPAT hydrobromide (Synonyms: S(-)-8-Hydroxy-2-dipropylaminotetralin hydrobromide)

Other Forms of S(-)-8-OH-DPAT hydrobromide:

S(-)-8-OH-DPAT hydrobromide Related Antibodies

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•Related Small Molecules:

•Related Proteins:

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Biological Activity

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References

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