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  3. Drug Derivative
  4. (S)-α-Methylbenzyl ricinoleamide

(S)-α-Methylbenzyl ricinoleamide (compound (R,S)-3d) is a fatty acid amide. (S)-α-Methylbenzyl ricinoleamide shows antiproliferative activity, inhibits the growth of human ovarian cancer cells NCI-ADR/RES and glioma cells U251 with GI50s???of 1.9 μg/mL and 3.6 μg/mL, respectively.

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(S)-α-Methylbenzyl ricinoleamide Chemical Structure

(S)-α-Methylbenzyl ricinoleamide Chemical Structure

CAS No. : 1246776-22-6

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(S)-α-Methylbenzyl ricinoleamide Related Antibodies

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Description

(S)-α-Methylbenzyl ricinoleamide (compound (R,S)-3d) is a fatty acid amide. (S)-α-Methylbenzyl ricinoleamide shows antiproliferative activity, inhibits the growth of human ovarian cancer cells NCI-ADR/RES and glioma cells U251 with GI50s???of 1.9 μg/mL and 3.6 μg/mL, respectively[1].

Cellular Effect
Cell Line Type Value Description References
786-0 GI50
6.7 μg/mL
Compound: (R,S)-3d
Antiproliferative activity against human 786-0 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human 786-0 cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
MCF7 GI50
5.1 μg/mL
Compound: (R,S)-3d
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
NCI/ADR-RES GI50
1.9 μg/mL
Compound: (R,S)-3d
Antiproliferative activity against human NCI/ADR-RES cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human NCI/ADR-RES cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
NCI-H460 GI50
8.3 μg/mL
Compound: (R,S)-3d
Antiproliferative activity against human NCI-H460 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human NCI-H460 cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
OVCAR-3 GI50
11.1 μg/mL
Compound: (R,S)-3d
Antiproliferative activity against human OVCAR3 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human OVCAR3 cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
PC-3 GI50
11.7 μg/mL
Compound: (R,S)-3d
Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
U-251 GI50
3.6 μg/mL
Compound: (R,S)-3d
Antiproliferative activity against human U251 cells after 48 hrs by sulforhodamine B assay
Antiproliferative activity against human U251 cells after 48 hrs by sulforhodamine B assay
[PMID: 25510639]
Molecular Weight

401.63

Formula

C26H43NO2
CAS No.
SMILES

CCCCCC[C@@H](O)C/C=C\CCCCCCCC(N[C@H](C1=CC=CC=C1)C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(S)-α-Methylbenzyl ricinoleamide Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S)-α-Methylbenzyl ricinoleamide1246776-22-6Drug DerivativeDrug derivativeantiproliferativeU251 cellsInhibitorinhibitorinhibit

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