2. GPCR/G Protein
  3. Taste Receptor
  4. S6821

S6821 is a TAS2R8 antagonist with IC50 value of 0.035 μM. S6821 is not found to be mutagenic or disruptive in vitro, nor is it found to induce micronucleus in bone marrow polychromatic erythrocytes in vivo.

For research use only. We do not sell to patients.

S6821 Chemical Structure

S6821 Chemical Structure

CAS No. : 1119831-25-2

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Based on 1 publication(s) in Google Scholar

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Description

S6821 is a TAS2R8 antagonist with IC50 value of 0.035 μM. S6821 is not found to be mutagenic or disruptive in vitro, nor is it found to induce micronucleus in bone marrow polychromatic erythrocytes in vivo[1].

IC50 & Target

IC50:TAS2R8 (0.035 μM)[1].
Molecular Weight

381.39

Formula

C19H19N5O4
CAS No.
Appearance

Solid

Color

Off-white to pink

SMILES

O=C1N(C2=CN(CC3=C(C)ON=C3C)N=C2)C(CN1CC4=CC(O)=CC=C4)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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S6821 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

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C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

S68211119831-25-2S 6821S-6821Taste Receptorcytochrome P450TAS2R8AntagonistS7958Inhibitorinhibitorinhibit

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