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  6. Saikogenin F

Saikogenin F  (Synonyms: (4R)-13,28-Epoxyolean-11-ene-3β,16β,23-triol)

Cat. No.: HY-N7670 Purity: 99.37%
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Saikogenin F exhibits anti-cancer activity.

For research use only. We do not sell to patients.

Saikogenin F Chemical Structure

Saikogenin F Chemical Structure

CAS No. : 14356-59-3

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Based on 1 publication(s) in Google Scholar

Saikogenin F Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

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Description

Saikogenin F exhibits anti-cancer activity[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
> 80 μM
Compound: 4
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Cytotoxicity against human A549 cells after 48 hrs by MTT assay
[PMID: 26883148]
Bcap37 IC50
> 80 μM
Compound: 4
Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay
Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay
[PMID: 26883148]
Hep 3B2 IC50
> 80 μM
Compound: 4
Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay
Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay
[PMID: 26883148]
HepG2 IC50
75.7 μM
Compound: 4
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
[PMID: 26883148]
MCF7 IC50
> 80 μM
Compound: 4
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
[PMID: 26883148]
In Vitro

Saikogenin F inhibits the proliferation of A549 cells with inhibition rates of 18.81%, 47.64% and 86.01% at concentrations of 50, 70 and 90 μg/mL, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Saikogenin F Related Antibodies
Molecular Weight

472.70

Formula

C30H48O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]1(C[C@@H]2O)[C@]3(C=C[C@@]4([H])[C@]1(CC[C@]([C@@](C)5CO)([H])[C@@]4(CC[C@@H]5O)C)C)[C@@](CC6(C)C)([H])[C@@]2(CC6)CO3
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Methanol : 25 mg/mL (52.89 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1155 mL 10.5775 mL 21.1551 mL
5 mM 0.4231 mL 2.1155 mL 4.2310 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Methanol 1 mM 2.1155 mL 10.5775 mL 21.1551 mL 52.8877 mL
5 mM 0.4231 mL 2.1155 mL 4.2310 mL 10.5775 mL
10 mM 0.2116 mL 1.0578 mL 2.1155 mL 5.2888 mL
15 mM 0.1410 mL 0.7052 mL 1.4103 mL 3.5258 mL
20 mM 0.1058 mL 0.5289 mL 1.0578 mL 2.6444 mL
25 mM 0.0846 mL 0.4231 mL 0.8462 mL 2.1155 mL
30 mM 0.0705 mL 0.3526 mL 0.7052 mL 1.7629 mL
40 mM 0.0529 mL 0.2644 mL 0.5289 mL 1.3222 mL
50 mM 0.0423 mL 0.2116 mL 0.4231 mL 1.0578 mL
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Saikogenin F Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Saikogenin F14356-59-3(4R)-13,28-Epoxyolean-11-ene-3β,16β,23-triolOthersInhibitorinhibitorinhibit

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