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  3. Salusin-α

Salusin-α is an endogenous bioactive peptide with hemodynamic and cell proliferation activities. Salusin-α can stimulate the proliferation of quiescent vascular smooth muscle cells (VSMCs) and fibroblasts, leading to a rapid and significant decrease in blood pressure and heart rate, but its effect is weaker than that of Salusin-β (HY-P10617). Salusin-α has potential application value in cardiovascular disease research.

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Salusin-α Chemical Structure

Salusin-α Chemical Structure

CAS No. : 624735-22-4

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Description

Salusin-α is an endogenous bioactive peptide with hemodynamic and cell proliferation activities. Salusin-α can stimulate the proliferation of quiescent vascular smooth muscle cells (VSMCs) and fibroblasts, leading to a rapid and significant decrease in blood pressure and heart rate, but its effect is weaker than that of Salusin-β (HY-P10617). Salusin-α has potential application value in cardiovascular disease research[1].

Molecular Weight

2602.99

Formula

C114H192N40O30

CAS No.
Sequence

Ser-Gly-Ala-Leu-Pro-Pro-Ala-Pro-Ala-Ala-Pro-Arg-Pro-Ala-Leu-Arg-Ala-Gln-Arg-Ala-Gly-Pro-Ala-Gly-Pro-Gly-Ala-Lys-NH2

Sequence Shortening

SGALPPAPAAPRPALRAQRAGPAGPGAK-NH2

SMILES

O=C(N1[C@@H](CCC1)C(N[C@@H](C)C(N2[C@@H](CCC2)C(N[C@@H](C)C(N[C@@H](C)C(N3[C@@H](CCC3)C(N[C@@H](CCCNC(N)=N)C(N4[C@@H](CCC4)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(NCC(N5[C@@H](CCC5)C(N[C@@H](C)C(NCC(N6[C@@H](CCC6)C(NCC(N[C@@H](C)C(N[C@H](C(N)=O)CCCCN)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]7N(CCC7)C([C@H](CC(C)C)NC([C@H](C)NC(CNC([C@@H](N)CO)=O)=O)=O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Salusin-α Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Salusin-α
Cat. No.:
HY-P10616
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